Methyl Acetoacetate 99%; CAS 105-45-3

• CAS No.: 105-45-3
• Formula: C5h8o3
• EINECS: 203-299-8
• Classification: Organic Analytical Reagents
• Grade: CP
• Specific Usage: For Biological Purpose, Technical Grade, Pratical Use, Pro Analysis, For Synthesis
• Model NO.: 105-45-3
• Content: Standard
• Usage: Laboratory Reagents, Analytical Reagents, Diagnostic Reagents, Teaching Reagents
• Source: Imported Reagents
• Habit Appellation: Fine Chemicals
• Application: Industry, Scientific Research, Health, Environmental Protection, Agriculture
• Property: Organic Reagent
• Transport Package: 500g
• Specification: 500g
• Trademark: Jianqi
• Origin: China
• HS Code: 2918300090
• Production Capacity: 50000mt/Year

Product Description

Methyl acetoacetate
3-Oxobutanoic Acid Methyl Ester is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.
Bacis information
CAS	105-45-3
English alias	Methyl 3-oxobutanoate;Butanoic acid, 3-oxo-, methyl ester;methyl 3-oxobutanoate;3-Oxobutyric acid methyl ester;Acetoacetic Acid Methyl Ester;Methyl 3-Oxobutyrate
Molecular formula	C5H8O3
Molecular weight	116.115
Accurate mass	116.047
Psa	43.37
Logp	0.1385
Numbering system
UNII
BRN number	506727
EINECS number	203-299-8
MDL number	MFCD00008784
RTECS number	AK5775000
PubChem number
Physicochemical property
Appearance and properties	Colorless liquid
Density	1.077
Boiling point	169-170°C70mm Hg(lit.)
Melting point	-28 °C
Freezing point
Flash point	158°F
Refractive index	n20/D 1.419(lit.)
Water solubility	460 g/L (20 ºC)
Stability	Stable under normal temperatures and pressures.
Storage conditions	Store in a cool, dry place. Keep container closed when not in use.
Safety information
RTECS number	AK5775000
Security description	S26
Danger category code	R36
WGK germany	1
Dangerous goods transport code
Customs code	2918300090
Danger mark	Xi
Production method and use
Production method	It is prepared by the reaction of diketene with methanol. Diketene and methanol were esterified with concentrated sulfuric acid as catalyst, and then the finished product was obtained by crude fractionation and rectification. Diketene is produced by cleavage of acetic acid. Refining method: In addition to containing free acids and alcohols, it also contains impurities such as acetone. When refining, it is dried with potassium carbonate or anhydrous sodium sulfate and then distilled under vacuum.
Use	It is used as a component of cellulose ether ester mixed solvent for the synthesis of pyrazoldone drugs and B vitamins